Břetislavova Street connects Jánský vršek with Tržiště and is one of the narrowest streets in Prague.

Records of its existence have been preserved since the 14th century, as many skirt makers worked and made woven goods here.

In the 17th century, it was the home to a lot of Prague’s carpentry. In the years 1839 – 1870 it was called Horský or Vrchová for its slope. The current name is most likely derived from the name of Prince Břetislav I. Another version states that it was named after a fire at the former inn at Břetislav, which was in the house No. 306 on the street.