In a lab at the Institute of Organic Chemistry and Biochemistry (IOCB) in Prague’s Dejvice district, scientists appear to have discovered the ‘Achilles heel’ of the virus.
“There is a family of viruses called the flaviviridae family, and Zika is one of those viruses,” said Dr. Radim Nencka. “We’ve been recently focused mostly on this family of viruses; in particular, we’ve been working on tick-borne encephalitis and also on the West Nile Virus, which is already connected or very similar to the Zika virus,” he added.
Czech scientist know which compounds are active against the virus and already achieved promising results, but they are still at the beginning of the fight: “We still need to modify the active compounds into so-called pro-drug forms. These pro-drugs should have improved pharmacological properties, should be better targeted to the organs in the body (and) should be slowly eliminated from the organism.”